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Cytokines and Inflammation
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Human Effector and Memory CD8+ T Cell Responses to Smallpox and Yellow Fever Vaccines
Joseph D. Miller, Robbert G. van der Most, Rama S. Akondy, John T. Glidewell, Sophia Albott, David Masopust, Kaja Murali-Krishna, Patryce L. Mahar, Srilatha Edupuganti, Susan Lalor, Stephanie Germon, Carlos Del Rio, Mark J. Mulligan, Silvija I. Staprans, John D. Altman, Mark B. Feinberg, and Rafi Ahmed
10.1016/j.immuni.2008.02.020
[Summary] [Full Text] [PDF] [Supplemental Data]
Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction
Qizhi Tang, Jason Y. Adams, Cristina Penaranda, Kristin Melli, Eliane Piaggio, Evridiki Sgouroudis, Ciriaco A. Piccirillo, Benoit L. Salomon, and Jeffrey A. Bluestone
10.1016/j.immuni.2008.03.016
[Summary] [Full Text] [PDF] [Supplemental Data]
Also In This Issue
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Basophils in the limelight Basophils tend to be the forgotten cells in immune responses. However, Karasuyama and colleagues highlight their critical importance in IgG-mediated anaphylaxis via their secretion of platelet activating factor. Preview by Galli and Franco. |
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Stopped by STAT5 Dendritic cell (DC) precursors express receptors for hematopoetic cytokines including Flt3-ligand and GM-CSF. Watowich and colleagues show how signaling from these two cytokines is integrated molecularly, and how the transcription factor STAT5 plays an inhibitory role in plasmacytoid DC development. Preview by Manz. |
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CD4+ T cell memory determinant The requirements for memory CD4+ T cell formation after an acute infection are not well defined. Bevan and colleagues find that T cell receptor avidity for antigen is likely to play a key role. |
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Watching for tumors NKG2D is an activating receptor commonly associated with NK cells and CD8+ T cells. By deleting this receptor from the animal, Raulet and colleagues determine that it is important in the in vivo surveillance against certain tumors. Preview by Ljunggren. |
Immunology@CellPress
See selected immunology-related articles from other Cell Press journals.
T-cell fate and function: PKC-θ and beyond
Benjamin J. Marsland and Manfred Kopf
Trends in Immunology
Les liaisons dangereuses: immunological synapse formation in animals and plants
Chian Kwon, Ralph Panstruga and Paul Schulze-Lefert
Trends in Immunology
Caspase-12 Modulates NOD Signaling and Regulates Antimicrobial Peptide Production and Mucosal Immunity
Philippe M. LeBlanc, Garabet Yeretssian, Nancy Rutherford, Karine Doiron, Amal Nadiri, Lei Zhu, Douglas R. Green, Samantha Gruenheid, and Maya Saleh
Cell Host & Microbe
Human Immunodeficiency Virus Type 1 Tat Protein Inhibits the SIRT1 Deacetylase and Induces T Cell Hyperactivation
Hye-Sook Kwon, Michael M. Brent, Ruth Getachew, Prerana Jayakumar, Lin-Feng Chen, Martina Schnolzer, Michael W. McBurney, Ronen Marmorstein, Warner C. Greene, and Melanie Ott
Cell Host & Microbe
Top 20 Articles
These are the Top 20 Papers (by download from the Immunity website for the last 30 days). You can see the summaries if you are registered or full text and PDFs if you have subscribed.
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