Articles Accessed Most Frequently

These are the Top 20 Papers (by download) for the 30 days preceding May 8, 2008. You can see the summaries if you are registered, or full text and PDFs if you have subscribed.

1.  The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation
Wenjun Ouyang, Jay K. Kolls and Yan Zheng
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
2.  Th17 Cell Differentiation: The Long and Winding Road
Mandy J. McGeachy and Daniel J. Cua
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
3.  Cytokine Signaling Modules in Inflammatory Responses
John J. O'Shea and Peter J. Murray
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
4.  Contextual Regulation of Inflammation: A Duet by Transforming Growth Factor-β and Interleukin-10
Ming O. Li and Richard A. Flavell
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
5.  Rapid Culling of the CD4+ T Cell Repertoire in the Transition from Effector to Memory
Matthew A. Williams, Eugene V. Ravkov and Michael J. Bevan
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
6.  Cytokines as Therapeutic Targets: Advances and Limitations
Clemens Scheinecker, Kurt Redlich and Josef S. Smolen
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
7.  NKG2D-Deficient Mice Are Defective in Tumor Surveillance in Models of Spontaneous Malignancy
Nadia Guerra, Ying Xim Tan, Nathalie T. Joncker, Augustine Choy, Fermin Gallardo, Na Xiong, Susan Knoblaugh, Dragana Cado, Norman R. Greenberg and David H. Raulet
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
8.  The Roaring Twenties
Richard M. Locksley
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
9.  Constitutive Crosspresentation of Tissue Antigens by Dendritic Cells Controls CD8+ T Cell Tolerance In Vivo
Nancy Luckashenak, Samira Schroeder, Katrin Endt, Darja Schmidt, Karsten Mahnke, Martin F. Bachmann, Peggy Marconi, Cornelia A. Deeg and Thomas Brocker
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
10.  The Signal Transducer STAT5 Inhibits Plasmacytoid Dendritic Cell Development by Suppressing Transcription Factor IRF8
Eiji Esashi, Yui-Hsi Wang, Olivia Perng, Xiao-Feng Qin, Yong-Jun Liu and Stephanie S. Watowich
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
11.  Innate Recognition of Viruses
Andreas Pichlmair and Caetano Reis e Sousa
[Summary]  [Fulltext]  [PDF] 
Sep 21, 2007 
27 (3)
12.  Apoptosis Regulators Fas and Bim Cooperate in Shutdown of Chronic Immune Responses and Prevention of Autoimmunity
Peter D. Hughes, Gabrielle T. Belz, Karen A. Fortner, Ralph C. Budd, Andreas Strasser and Philippe Bouillet
[Summary]  [Fulltext]  [PDF] 
Feb 15, 2008 
28 (2)
13.  Basophils Play a Pivotal Role in Immunoglobulin-G-Mediated but Not Immunoglobulin-E-Mediated Systemic Anaphylaxis
Yusuke Tsujimura, Kazushige Obata, Kaori Mukai, Hideo Shindou, Masayuki Yoshida, Hideto Nishikado, Yohei Kawano, Yoshiyuki Minegishi, Takao Shimizu and Hajime Karasuyama
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
14.  Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces
Yuri P. Rubtsov, Jeffrey P. Rasmussen, Emil Y. Chi, Jason Fontenot, Luca Castelli, Xin Ye, Piper Treuting, Lisa Siewe, Axel Roers, William R. Henderson, Werner Muller and Alexander Y. Rudensky
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
15.  Interleukin-23 Restrains Regulatory T Cell Activity to Drive T Cell-Dependent Colitis
Ana Izcue, Sophie Hue, Sofia Buonocore, Carolina V. Arancibia-Cárcamo, Philip P. Ahern, Yoichiro Iwakura, Kevin J. Maloy and Fiona Powrie
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
16.  Combined Deficiency of Proapoptotic Regulators Bim and Fas Results in the Early Onset of Systemic Autoimmunity
Jack Hutcheson, John C. Scatizzi, Akbar M. Siddiqui, G. Kenneth Haines, Tianfu Wu, Quan-Zhen Li, Laurie S. Davis, Chandra Mohan and Harris Perlman
[Summary]  [Fulltext]  [PDF] 
Feb 15, 2008 
28 (2)
17.  B Cell Development: Important Work for ERK
Michael R. Gold
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
18.  Apoptosis Regulators Bim and Fas Function Concurrently to Control Autoimmunity and CD8+ T Cell Contraction
Ashley E. Weant, Ryan D. Michalek, Islam U. Khan, Beth C. Holbrook, Mark C. Willingham and Jason M. Grayson
[Summary]  [Fulltext]  [PDF] 
Feb 15, 2008 
28 (2)
19.  Erk Kinases Link Pre-B Cell Receptor Signaling to Transcriptional Events Required for Early B Cell Expansion
Tomoharu Yasuda, Hideki Sanjo, Gilles Pagès, Yohei Kawano, Hajime Karasuyama, Jacques Pouysségur, Masato Ogata and Tomohiro Kurosaki
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)
20.  Cancer Immunosurveillance: NKG2D Breaks Cover
Hans-Gustaf Ljunggren
[Summary]  [Fulltext]  [PDF] 
Apr 11, 2008 
28 (4)